MergedTeachingElementsClemson University Courses

Dr. Lawton-Rauh developed, continuously updates, and teaches the following:

See course description for GEN-4100/Honors4100/6100 cross-listed course further down page

GEN 4100: Fundamentals of Genetics I: Population and Quantitative Genetics (Spring semesters)
GEN Honors410 / GEN 6100: Cross-listed Graduate and Honors Population and Quantitative Genetics (Spring semesters)
GEN 4110 / 6110: Population and Quantitative Genetics Laboratory Course (Spring semesters). PhD students that are on Teaching Assistantships in the Lawton-Rauh lab often TA this course.

Other types of courses that Dr. Lawton-Rauh would like to teach:

— Methods of Analysis in Population Genetics, Molecular Evolution, and Quantitative Genomics (developed and taught previously at Clemson University)
— Domestication and Diversity Genomics

Dr. Lawton-Rauh also teaches:

GEN 4910, BIOCH 4910, and Honors sections: Directed Undergraduate Research
GEN 9910: Genetics and Biochemistry Graduate Student Research
GEN 8140: Advanced Genetics (contributes the ‘Population, Quantitative Genetics, Phylogenetics, and Molecular Evolution’ course sections; folds in genome-wide association studies (GWAS), genome prediction and genome selection principles…all applicable to personalized medicine, optimized agriculture, and resilient ecosystem health)

GEN-4100 Population and Quantitative Genetics @ Clemson University Course description:

This course provides in-depth dissection of equilibrium and non-equilibrium processes that shape genetic and quantitative phenotypic variation. You will learn how these processes are formalized into testable models and how to statistically identify which processes are most likely operating in different cases. You will learn about specific equilibrium and non-equilibrium processes that occur at different levels of biological organization, from single gene/two-allele and multiple gene/multiple allele levels, upwards to the genome-wide and chromosomal levels. You will learn how these processes lead to different patterns of variation over space and time and how to estimate and interpret these parameters from the population level to the among-species level. You will become conversant in model testing and become critical of underlying genetic assumptions used in models and interpretations of results. Specifically, you will learn how to apply population and quantitative genetic theories tools to examine the effects of: natural and artificial/managed selection, and multi-locus, multi-allele Hardy-Weinberg violations on genetic variation and the heritability of quantitative genetic traits. You will understand the impact of the processes of genetic drift, population size, and gene flow, and how these processes interact with linkage disequilibrium and are used in human disease mapping, cultivated species breeding, and natural selection in wild populations. The overall goals are to understand the relationships among population-level genetic variation, quantitative trait variation, molecular evolution (diversification of genes and genomes) and trait variation (molecular and morphological phenotypes) and ultimately how to examine real-world data to determine the best fit model(s) explaining observed trait and genetic and ultimately genomic variation.

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